Modelling and simulation of blood collection systems: improvement of human resources allocation for better cost-effectiveness and reduction of candidate donor abandonment

Edgar Alfonso Lizarazo (1, 2, 3, 4, 5) , Xiaolan Xie (1, 2, 3, 4) , Vincent Augusto (1, 2, 3, 4) , Olivier Garraud (6, 2, 7)

1 CIS-ENSMSE - Centre Ingénierie et Santé
2 IFRESIS - Institut Fédératif de Recherche en Sciences et Ingénierie de la Santé
3 LIMOS - Laboratoire d'Informatique, de Modélisation et d'optimisation des Systèmes
4 I4S-ENSMSE - Ingénierie des systèmes de soins et des services de santé
5 GLS - Group Logistics Systems
6 GIMAP - Groupe Immunité des Muqueuses et Agents Pathogènes
7 EFS-AL - EFS-Auvergne Loire

Formal Petri net models were used to describe all relevant donor flows of the various blood collection systems; the Petri net models were converted onto discrete-event simulation models, allowing the evaluation of a large number of scenarios and configurations of blood collection systems. Quantitative models were proposed that encompassed all components of the blood collection systems, such as the donor arrival process, resource capacities and performance indicators. Appropriate experimental designs and cost-effectiveness analyses were used to determine the best configurations of human resources and donor appointment strategies.

Mots clés: blood donor flow management; discrete-event simulation; health system cost-effectiveness; petri nets; transfusion

Domaines: Génie des procédés; Recherche opérationnelle [math.OC]

Edgar Alfonso Lizarazo, Xiaolan Xie, Vincent Augusto, Olivier Garraud. Modelling and simulation of blood collection systems: improvement of human resources allocation for better cost-effectiveness and reduction of candidate donor abandonment. Vox Sanguinis, 2013, 104 (3), pp.225-233. ⟨10.1111/vox.12001⟩. ⟨hal-00840560⟩